There is extensive evidence for early onset and persistent cognitive impairments in schizophrenia (Green et al., 2004; Keefe et al., 2005). Such deficits are considered to be a major cause of functional impairment and a quest to understand pathogenic mechanisms of cognitive deficits remains a priority. Though the association between cognitive ability and psychosis is known (Morgan et al., 2014) with evidence supporting a shared genetic basis for cognitive ability and neuropsychiatric illnesses such as schizophrenia (Hagenaars et al., 2016; Hill et al., 2016), the exact nature of this relationship remains obscure (Johnson et al., 2016).
