Currently, these tools are not ready for clinical use. If we reach the point where social, clinical, and genetic information become sufficiently powerful, we must recognize that identifying persons for early intervention carries a significant risk. Screening for social determinants has the potential for unintended consequences, including further stigmatization [61]. Genetic information has even more potential for abuse. Policy makers must ensure that there is comprehensive legal protection against discrimination using any form of information. Additionally, any attempt to use social, clinical, or genetic information for targeted intervention or identification in a clinical setting must be done so in a patient-centered approach, rather than any “one-size fits all” that exclude patients from their own healthcare decisions [62].