Chunk #14 — Materials and methods — Unsupervised learning to determine POU clustering

Source

Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry.

Embedded

yes

Text

The product of HCA is a dendrogram, formed with multiple brackets called “branches”. Phenotypes on the same branch are more similar to each other based on their pairwise genetic associations with each other and with all other phenotypes on that branch. Branches can form subbranches of more specific clustering.