Interview Schedule for Children (DISC; Shaffer et al. 2000) for those under 17 years of age. At wave 1, 23% of the sample met the criteria for lifetime major depression, 11% for generalized anxiety and 57% for antisocial personality disorder (only measured in the adult portion of the sample). Subjects were assessed for lifetime ND symptoms with the CIDI-SAM, and DNA was voluntary obtained through either buccal cells or blood. All recruitment, assessment, and DNA collection procedures were approved by the IRBs at the University of Colorado and University of California. A similar analytical approach was taken with the GADD sample as the CADD. Briefly, only participants who were 17 or older at the time of assessment were included in the analysis. Genotypic data available for all participants were included in the analysis, but phenotypic data were included only for the offspring generation.
