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Chunk #19 — Results — Analyses Predicting Intercept, Slope, and Quadratic Curvature of the Longitudinal Course of Heavy Episodic Drinking

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The Impact of Polygenic Risk, Parental Separation, and Parental Relationship Discord on Heavy Episodic Drinking Across Adolescence and Young Adulthood in a High-Risk Sample.
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Q–0.002[–0.006, 0.001]–0.001[–0.004, 0.003]PGSPAU I0.012[–0.108, 0.131]0.012[–0.120, 0.143] S–0.000[–0.037, 0.036]0.007[–0.027, 0.042] Q0.000[–0.002, 0.002]0.000[–0.001, 0.002]Separation/discord I–0.021[–0.261, 0.218]–0.068[–0.180, 0.043] S0.013[–0.060, 0.086]0.062[0.034, 0.090] Q0.000[–0.004, 0.004]–0.003[–0.004, –0.001]Note: Polygenic score residualized on the first 10 genetic similarity principal components. Separate models were run for parental separation and parental relationship discord. All models included parental education as a covariate for initial status, whereas sex was included for both initial status and change over time. Boldface type indicates estimate p < .05. I = intercept; PGSPAU = problematic alcohol use polygenic score; Q = quadratic slope; S = linear slope.