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Chunk #8 — Results — Association results for PAU

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Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.
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Examination of the 66 associated genes for known drug-gene interactions through the Drug Gene Interaction Database v3.0.2 [11] showed 327 interactions between 16 genes and 325 drugs (Supplementary Table 5). Of these 16 genes with interactions, DRD2 had the most drug interactions (n = 177), followed by BDNF (n = 68) and PDE4B (n = 36).