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Chunk #35 — Discussion

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Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls.
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for the presence of these more complex, and as yet hypothetic genotypic effects on structural maturation. Finally, our approach to image analysis focused in CT and different methods will be required to determine how Val158Met genotype modulates other aspects of cortical morphometry such as surface area and gyrification, which are known to be shaped by genetic influences that are partially distinct from those that influence CT (Panizzon et al., 2009).