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Chunk #20 — IMPULSIVITY AND DECISION-MAKING IN BIPOLAR DISORDER

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Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholism.
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To summarize, impulsivity, involving poorly regulated action, is pervasive in bipolar disorder and may be one of the basic mechanisms of the illness. It has a state-dependent component that correlates differentially with depressive or manic symptoms. This is superimposed on trait-like features that include the integrated impulsivity reflected in total scores of the BIS-11, problems with response inhibition, and problems with tolerating delays before responding for rewards. There is also some evidence that these features of the disorder involve increased sensitivity to catecholamine activity.