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Chunk #10 — Online Methods: — Testing cohort

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Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.
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Diagnosis of prevalent disease was based on a composite of data from self-report in an interview with a trained nurse, electronic health record (EHR) information including inpatient International Classification of Disease (ICD-10) diagnosis codes and Office of Population and Censuses Surveys (OPCS-4) procedure codes.