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Chunk #8 — Results

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Common variant at 16p11.2 conferring risk of psychosis.
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We assembled a psychosis (schizophrenia, bipolar disorder and related psychoses) primary follow-up dataset made up of 36 study groups containing a total of 18,583 cases, 68,516 controls and 808 unaffected family members (Supplementary Table 1). In each study group, allelic association analysis was carried out for 39 SNPs from 33 genomic regions (these SNPs covered P values less than 1 × 10−4 in the SGENE-plus+ISC+MGS meta-analysis at r2 = 0.3). Results from the various study groups were combined using inverse-variance weighted meta-analysis.