Chunk #8 — Materials and Methods — GENOTYPING — — STAR*D cases

Source

Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.

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Genotyping was conducted for 754 cases by Affymetrix, Inc., with the Affymetrix GeneChip Human Mapping 500K Array Set and genotypes called with the Bayesian Robust Linear Model with Mahalanobis distance classifier (BRLMM)27. We genotyped the remaining 746 cases with the Affymetrix Genome-Wide Human SNP 5.0 Array and called genotypes with the updated BRLMM-P algorithm. There were 500,568 SNPs that were assayed by both arrays.