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Chunk #17 — RESULTS — Group network connectivity analysis

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Reduced left executive control network functional connectivity is associated with alcohol use disorders.
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For all ALC, LECN network strength was negatively correlated with both ICS-FC and AUDIT scores (Table 3) remaining significant when controlling for FD, gender and age (r = −0.125, p = 0.015 and r = −0.158, p=0.002 respectively), which suggests that motion, gender nor age were driving the results. To further insure that age was not driving these effects, the sample was split at 40 years, finding the same negative relationships between LECN connectivity and ICS-FC and AUDIT within both groups: Young ALC (n = 307, Age = 27.2(5.1)): r = −0.161, p = 0.005 and r = −0.177, p=0.002 respectively; Old ALC (n = 76, Age = 46.7(4.5)): r = −0.299, p=0.009 and r = −0.264, p = 0.021 respectively. Connectivity strength of the other networks identified in the MANCOVA was not related to either ICS-FC or AUDIT.