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Chunk #43 — Results — FinnTwin12 Analyses — Testing for Moderated Indirect Effects in FinnTwin12

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Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2.
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We tested whether life events and GABRA2 interacted to predict adolescent externalizing while simultaneously controlling for parental externalizing behavior. The results from these analyses are shown as a series of models in Tables 8 and 9. In terms of main effects, adolescents who were male, whose parents had higher parental antisocial behavior, and who experienced more life events had higher teacher-reported externalizing (see Model 1 in Tables 8 and 9). Missing a parental antisocial behavior or alcohol dependence symptom report, parental alcohol dependence symptoms, and GABRA2 genotype were not significantly associated with teacher-reported externalizing. As shown in Model 2 of Tables 8 and 9, the life events × GABRA2 interaction effects did not reach strict (p < 0.05) statistical significance in either the parental antisocial behavior or alcohol dependence symptoms models (the p values for the interaction effects ranged were 0.09 and 0.11, respectively). Figure 4 depicts adolescent externalizing as a function of life events and GABRA2 genotype for the model that included parental antisocial behavior. A consistent pattern of effects was found for the model that included parental alcohol