0.09 and 0.11, respectively). Figure 4 depicts adolescent externalizing as a function of life events and GABRA2 genotype for the model that included parental antisocial behavior. A consistent pattern of effects was found for the model that included parental alcohol dependence symptoms (available upon request from the first author). And, as shown in Figure 5, the direction of these effects mirrored the results from the CDP sample. In the model that included parental antisocial behavior (Panel A) life events predicted subsequent teacher-reported externalizing for those with no copies of the minor allele (β = 0.18, 95% CI [0.06, 0.30]), but not for those with one or two copies of the minor allele (β1MA = 0.08, 95% CI [−0.02, 0.17]); β2MA = 0.03, 95% CI [−0.14, 0.21]). Similarly, in the model that included parental alcohol dependence symptoms (Panel B), life events predicted subsequent teacher-reported externalizing for those with no copies of the minor allele (β = 0.11, 95% CI [0.04, 0.17]), but not for those with one or two copies of the minor allele (β1MA = 0.04, 95% CI [−0.01, 0.09]); β2MA = 0.02, 95% CI [−0.08, 0.12]).
