cleaned GWAS data files, meta-analysis results were filtered to exclude any variants with N < 30,000. Consequently, we removed 2,134,049 SNPs, resulting in 7,392,849 SNPs available for analysis. To investigate sex-specific genetic effects, we also ran the meta-analysis in the datasets for which we had sex-specific data (N = 50,252). However, sex-specific SNP heritabilities, as estimated with LD Score Regression, were small and non-significant (3.7% (s.e. = 2.2%) for males and 1.0% (s.e. = 1.8%) for females). Due to the non-significant sex-specific heritability estimates, the genetic correlation of male and female ASB could not be estimated reliably and no sex-specific follow-up analyses were conducted.
