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Chunk #20 — RESULTS

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Externalizing disorders in American Indians: comorbidity and a genome wide linkage analysis.
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Table 4 presents all loci identified with LOD scores above 1.5 for comparison with other genetic studies that have identified loci for externalizing phenotypes in similar regions of the genome. One region of the genome, on chromome 12, was identified previously in a genome scan for a phenotype of “the severity of alcohol dependence drinking symptomatology” in this American Indian population (Ehlers et al., 2004c). Bivariate analysis of the ASPD/CD phenotype with the severity of alcohol dependence drinking symptomatology phenotype (LOD score 1.7) produced a combined maximum LOD score of 2.7. Complete pleiotropy can be excluded by this analysis, but the analysis had insufficient power to exclude coincident linkage.