Next, we examined whether these modes of covariation were localized in particular DMN subregions. To aid interpretation, we visualized where average changes of coupling between DMN subregions were most related to between-network coupling changes. This summary highlights the DMN subregions most consistently associated with changes of global network connectivity across all significant modes (Fig. 3A). Analogous to previous research (22), the cumulative increases and decreases of DMN subregion connectivity were examined separately.