Based on the availability and the type of experimental supports for miRNA–mRNA interaction, miRNA target sites were classified as LT (binding is supported from a low-throughput experiment), HT (binding is supported by a high-throughput experiment), HTL (the specific binding location is supported by a high-throughput experiment), LTL (the specific binding location is supported by a low-throughput experiment) and N (no experimental support) (20). We have collected >14 000 new experimentally supported miRNA–mRNA interactions from two recently updated databases, miRecords (35) and miRTarBase (36). The PolymiRTS database now contains 2944 records for experimentally supported miRNA target sites with polymorphisms.
