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Chunk #10 — 2. Methods — 2.2. Childhood Trauma Questionnaire (CTQ)

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Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.
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A dichotomous total CTQ score was derived solely to illustrate the direction of interaction effects on suicide attempt. A total CTQ score ≥ 1 SD above the mean CTQ score of non-substance dependent/no suicide attempt participants (36.49 (11.67), i.e. ≥48) was designated ‘high trauma’ (N = 290); lower total CTQ scores (<48) were designated ‘low trauma’ (N = 590). This approach has been used in our earlier studies: Enoch et al. (2010) and Roy et al. (2010).