Chunk #33 — Methods and results — Testing for significance of gene-environment interaction effects using the reparameterized equation

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Testing for measured gene-environment interaction: problems with the use of cross-product terms and a regression model reparameterization solution.

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The slope difference A between G = 1 and G = 0 is A≡(γ2+γ3+γ5)−γ2=γ3+γ5.