Chunk #34 — Methods and results — Testing for significance of gene-environment interaction effects using the reparameterized equation

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Testing for measured gene-environment interaction: problems with the use of cross-product terms and a regression model reparameterization solution.

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Similarly, slope differences between G = 2 and G = 1, and between G = 2 and G = 0 are, respectively, B≡(γ2+2γ3+4γ5)−(γ2+γ3+γ5)=γ3+3γ5, and C≡(γ2+2γ3+4γ5)−γ2=2γ3+4γ5.