Behavioral variables that might mediate links between brain structure and alcohol consumption (i.e., IQ, delay discounting, self-reported impulsivity, negative urgency, and neuroticism) and that were available in the DNS and HCP data sets and were tested for association with GMV. Despite nominally significant associations in the DNS between delay discounting and IQ and GMV of the right frontal cortex, none of these associations replicated within the HCP data or were robust to multiple testing correction (see Supplement 1, Tables S9, S10 in Supplement 1).
