Control and experimental groups were age-matched for further control over possible age-related confounds (Table 1). Many of the COGA families were densely affected with AUD, so that COGA participants, including unaffected individuals used as controls in this study, were more likely to come from families at higher risk for AUD than the general population.Table 1Participant demographics.Table 1WomenMenAUDUnaffectedAUDUnaffectedAges mean ± SEM36.6 ± 6.536.6 ± 6.534.8 ± 6.534.1 ± 7.0 (N = )(180)(180)(203)(203)Age matching: t-statistic0.01.0235 (p-value)(p = 1.0)(p = 0.3067)Ever drunk alcohol (yes/no)180/0170/10203/0190/13Age of first drink mean ± SEM15.6 ± 0.319.6 ± 0.414.5 ± 0.218.2 ± 0.3Years of AUD diagnosis mean ± SEM13.1 ± 0.5NA12.9 ± 0.4NA
