The same model was used to test for an effect of the FTO×PA interaction on the odds of obesity (BMI≥30 versus BMI<25 kg/m2) and overweight (BMI≥25 versus BMI<25 kg/m2) in adults, using normal-weight individuals as the reference group and testing for an additive effect in the “log odds” scale. In addition, each study tested the main effect of the FTO SNP on each outcome in the whole study population and in the inactive and physically active subgroups separately, using the model (2)
