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Chunk #43 — Discussion

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Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease.
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Moreover, we found that other psychiatric traits implicated largely similar cell types. These biological findings are consistent with genetic and epidemiological evidence of a general psychopathy factor underlying diverse clinical psychiatric disorders 21,57,58. Although intelligence and educational attainment implicated similar cell types, conditional analyses showed that the same cell types were implicated for different reasons. This suggests that different sets of genes highly specific to the same cell types contribute independently to schizophrenia and cognitive traits.