behavioral variation is becoming increasingly clear. For example, blocking beta oscillations (13–30 Hz) in the subthalamic nucleus (STN) of patients with Parkinson's disease during deep brain stimulation treatment can result in relieving bradykinetic symptoms (Engel & Fries, 2010; Swann et al., 2011); moreover, stimulation only during periods of elevated beta activity in the STN is sufficient to obtain symptom relief (Little & Brown, 2014). This finding led to the conclusion that a surplus STN beta activity causes bradykinesia (Brown, 2006). Other examples using optogenetic driving of oscillations in the mouse brain further highlight the contribution of oscillatory activity to communication and behavior (Cho et al., 2015; Karalis et al., 2016).
