of many articles that discuss them as a group. In fact, most of the family members operate in quite different pathways. In future, more sophisticated natural language processing technology may be applied to reduce these effects. At present, a concept overlap weighting scheme that emphasizes relationships to 'hub' proteins is used, and ensures that proteins weakly linked to these are included. A weighting scheme that takes into account the number of papers published on a gene may further improve inclusion of relevant weak links. The analysis is limited to abstracts already annotated as relevant to a particular gene. Extension to all pubmed abstracts (currently about 8.5 million) is desirable. In practice, the resource is very effective at narrowing down the amount of literature a user must consult in arriving at an informed position, our main goal.
