Subjects of European ancestry with genotype data and relapse data were analyzed (N=1,073). Table S1 shows demographics. Haplotype counts and frequencies in the UW-TTURC sample were: GC (20.8%), GT (43.7%), and AC (35.5%), and they were labeled again as H1, H2, and H3, respectively. In this treatment seeking sample, CPD was associated with the three haplotypes after adjusting for age and gender (Wald=7.15, df=2, omnibus-p=0.028 for the overall haplotype effect), but this effect was modest in this heavy smoking cohort (Table S2).
