Chunk #8 — Materials and Methods — Animals

Source

Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome.

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yes

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The experiments were conducted in accordance with the National Institutes of Health guidelines and with an approved protocol from the University of California San Diego (UCSD) Institutional Animal Care and Use Committee.