et al., 2010). A lower number of drinks needed for effects (a higher LR per drink) might also have contributed to the greater ability of High-Risk Drinkers, compared to Problem drinkers, to avoid multiple alcohol problems. The contributions by LR to predicting outcomes were observed even after considering age, sex, as well as drinking and drug use histories in the same analyses, indicating that LR may have added unique information for predicting later outcomes. The fact that both SRE5 (potentially relating to levels of reaction to alcohol early in the career and before acquired intersession tolerance is likely to have developed) and SRET (a measure that is likely to include both initial sensitivity and acquired tolerance) contributed to differentiating between outcome groups is also of interest, although the fact that these two measures were not always concordant is a reminder that they are likely to measure related, but not identical phenomena (Schuckit, 2018).
