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Chunk #21 — Results — Functionally informed fine-mapping of 49 complex traits

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Functionally informed fine-mapping and polygenic localization of complex trait heritability.
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In summary, we leveraged the improved power of PolyFun + SuSiE to robustly identify thousands of fine-mapped SNPs, providing a rich set of potential candidates for functional follow-up. Our results further indicate pervasive pleiotropy, with many SNPs fine-mapped for two or more genetically uncorrelated traits.