Correlations among the alcohol-related outcome variables were also found to be highly significantly related with one another, which is in line with the research showing heavy and high-intensity drinking is associated with alcohol-related negative consequences such as withdrawal symptoms and health issues [166,167]. Furthermore, the significant positive correlation between the two personality traits, namely, neuroticism and harm avoidance, is also backed by the evidence that both traits underlie negative emotions such as fear, shyness, and worry and are regulated by serotonin and opiate pathways [168]. Lastly, it was a rather unexpected finding that there were no highly significant correlations across the domains (e.g., functional connectivity vs. personality), likely because of very low levels of correlation across the domains due to insufficient statistical power to detect the subtle associations among features from different categories of predictors.
