other genes that are located within its boundaries. RefSeqGene records are reviewed initially by locus-specific databases and NCBI staff. RefSeqGene is a member of the LRG collaboration (7) which provides additional review of the sequence data before adding an LRG accession. A recent work focus expanded the number of RefSeqGene records to represent all genes for which at least two clinical tests have been submitted to the NIH Genetic Testing Registry (GTR). At this time there are 5596 RefSeqGene records, of which 633 have an LRG accession. RefSeqGene records can be retrieved by searching the Nucleotide database with ‘refseqgene[keyword]’, by their LRG accessions, by browsing the RefSeqGene web site (www.ncbi.nlm.nih.gov/refseq/rsg/), or by FTP (ftp://ftp.ncbi.nlm.nih.gov/refseq/H_sapiens/RefSeqGene/).
