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Chunk #5 — Materials and Methods — Subjects

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Electroencephalographic Cross-Frequency Coupling as a Sign of Disease Progression in Patients With Mild Cognitive Impairment: A Pilot Study.
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Data have also been presented in other studies using other types of analyses (Musaeus et al., 2018b, 2019a,b; Schjonning Nielsen et al., 2018), and the data were in part collected as a large multicenter study (Engedal et al., 2015). This cohort study was conducted at two Danish memory clinics and involved patients who were diagnosed with either MCI or mild AD and a baseline Mini-Mental State Examination (MMSE) score of ≥22. The following exclusion criteria were used: (1) no close relatives who wished to participate, (2) participating in intervention studies or (3) suffered from other neurological, psychiatric, or other severe diseases, (4) received sedative medication, and (5) had any past or current addiction to alcohol or medications.