Visualization of the data with regard to the distribution of CNVs across disorders for strict criteria using CNV groupings also demonstrated a high degree of overlap between all disorders and ID, yet less so than when visualized by gene groupings. ID was associated with 46.2% (6 of 13) of CNVs associated with autism, 43.0% (9 of 21) of CNVs in schizophrenia, and 100% (3 of 3) of CNVs in epilepsy. Almost half of ASD CNVs (6 of 13, 46.2%) and all epilepsy CNVs (3 of 3, 100%) were also found in schizophrenia. There was no overlap among significant ASD and epilepsy CNVs using strict criteria. The distinction between the extent of overlap across disorders based on gene-content as compared to based on CNVs appears to reflect the genic content of CNVs implicated in each disorder under strict criteria. Specifically, the average number of genes per CNV for each disorder was as follows: ID—49 genes; ASD—28 genes; schizophrenia—32 genes; and epilepsy—47 genes. Notably, ID CNVs were significantly larger than ASD CNVs (p=.009) (Figure 2). Also CNVs were categorized as either deletion
