has proven to be a useful strategy to increase transgene expression following transplantation and removal of AZA (19). In the AZA treated NSCs, a disruption of 3me-H3K27 marks and DNMT1 distribution was also observed, which appears to be in line with retarded migration and differentiation. Further support of the role of histone marks and DNA methylation marks on differentiation is shown by their intranuclear / intracellular translocation indicated in the section below.
