Chunk #29 — Results — Lysine residues 21 and 109 direct ASC’s SUMOylation and oligomerization

Source

Inflammasome activity is controlled by ZBTB16-dependent SUMOylation of ASC.

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yes

Text

These data identify that ZBTB16 promotes inflammasome assembly by controlling the modification of the adaptor protein ASC with SUMO1 on lysine residues at positions 21 and/or 109.