Smokers with the rs3800373*C allele, compared to those homozygous for the A allele, reported lower MNWS scores at baseline (main effect for group: F(1,164)=7.37; P<0.010), but not after nicotine (Figure 1A). FKBP5 mRNA was not associated with MNWS, nor was FKBP5 genotype or mRNA associated with QSU or PANAS scores.