Finally, a more general version of the MetaGAP calculator is provided in the form of MATLAB code (www.mathworks.com), also available at www.devlaming.eu. This code can be used in case one desires to specify a more versatile genetic-correlation matrix, where the CGR can differ between all pairs of studies. Therefore, this implementation requires the user to specify a full (C+1)-by-(C+1) correlation matrix. Calculations in this code are also fully in line with the generic expressions in S1 Derivations and S2 Derivations.