The Brazilian sample consisted of 126 patients with BD (23 men and 103 women; mean age at interview 43.03 ± 10.7 years old; 84 BD type I, 40 BD type II and 2 BD type NOS). All patients completed the CTQ with a mean total score of 52.39 ± 20.4. One hundred and twenty two patients were genotyped for the 5HTTLPR l/s variant and for the rs25531 (4 DNA failed to be amplified by PCR). The distribution of genotypes were the following : 30 patients with ‘LL’ genotype, 63 with ‘LS’ genotype and 29 with ‘SS’ genotype. The SLC6A4 promoter variants genotypic frequencies were in Hardy-Weinberg equilibrium (p = 0.82).
