The replication sample differed from the initial one for gender distribution (p < 0.001), BD subtypes distribution (p = 0.02) and CTQ total score (p < 0.001); this corresponded to a Brazilian sample consisting of more females, more BD type II and with a higher CTQ total score. The two samples were similar for age at interview (p = 0.99), age at onset (p = 0.59) and genotypes distribution (p = 0.27).