did not report the direction of individual effects of the integrated coefficients (FA, MD, RD) [45]. The findings of this study can thus only be interpreted as a change in fiber integrity in AUD. Regarding the robustness of the meta-analytic results, the ALE clusters remained significant after adding 5 up to 283% noise studies (FSN). The calculated FSN values for each cluster are presented in the last column of Table 2.