Chunk #33 — Results — Polygenic scores from SCZ applied to clinical dimensions in BP

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Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.

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In the BP samples, we were limited to only a dichotomous rating about the presence or absence of psychosis. We calculated SCZ polygenic risk scores using our full independent SCZ dataset in all BP cases and tested for a correlation between presence of psychosis and SCZ polygenic score as described above. No such correlation was observed. (data not shown)