sought to understand the effect that individuals with both high BP polygenic score and high manic factor score had on our results. We removed 186 individuals with BP polygenic score and manic factor score one standard deviation from the mean and repeated our analyses. We identify the same six genome-wide significant hits, nearly identical SCZ odds ratios and equal if not slightly more significant discrimination ability in our between disorder BP vs SCZ polygenic analysis (Supplementary Table 7, Supplementary Figures 3-4)
