statistical tests across variables. Therefore, our findings require independent replication. However, some of our statistically significant findings would stand up to correction for multiple comparisons; for example, the associations of moderate and severe risk of problem gambling with suicidal ideation or attempts and younger age at illness onset. Finally, the cross-sectional design of the study does not allow us to make inferences about causality, that is, whether mood dysregulation in bipolar disorder contributes to problem gambling, or whether problem gambling is used as a way of regulating mood as suggested by Lloyd et al.12
