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Chunk #46 — INITIAL GRAPH THEORETIC STUDIES OF DEVELOPMENT

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The development of human functional brain networks.
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in fMRI studies, such that ROIs in the CO network tended to display sustained activity during tasks, while ROIs in the FP network tended to activate more transiently, linking the functional properties of ROIs to their properties as nodes within rs-fcMRI networks. Children and adults differ behaviorally in task performance (Brown et al., 2005; Church et al., 2010; Schlaggar et al., 2002), and fMRI studies have documented developmental differences in activity in task control regions during task performance (Velanova et al., 2009), leading Fair et al. to examine task control regions for developmental changes in functional network structure. To accomplish this, 39 task control regions were examined as graphs in rs-fcMRI data from 210 subjects ages 7–35 years. Nodes were formed by modeling ROIs as 10 mm diameter spheres, and edges were defined as the Pearson correlations between node rs-fcMRI timecourses.