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Chunk #55 — Results — Central Nervous Systems Neurons

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Molecular Architecture of the Mouse Nervous System.
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In the hindbrain (15 types not including cerebellum), all inhibitory neurons were glycinergic (GLYT1, GLYT2, or both), and excitatory neurons were a mix of VGLUT1 and VGLUT2. We identified six cell types in the cerebellum, of which five are previously known: Purkinje cells, granular cells, granular layer interneurons, molecular layer interneurons, and granular cell neuroblasts. A sixth cell type (MEINH1), curiously, was found in the midbrain but was molecularly indistinguishable (Figure S1E) from cerebellum molecular layer interneurons (CBINH1). It is the only example of a neuronal cell type found in two different and distant regions.