Chunk #31 — 3. Disruption of functional networks is associated with clinical impairment — 3.3 Parkinson's Disease and Dementia with Lewy bodies

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Functional network disruption in the degenerative dementias.

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Graph theory studies of network organization in PD, PDD and DLB are scarce. One study investigated motor circuits connectivity in PD, reporting abnormal basal ganglia-thalamocortical connectivity in line with previous fMRI studies,120 and another study showed reduced global efficiency.121