Chunk #25 — Materials and methods — Data sources — Pipeline data

Source

Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

Embedded

yes

Text

Pharmaprojects gene targets were mapped from Entrez to ensembl IDs. Drugs with non-human and xMHC targets were excluded (following the original analysis) as were a small number of drugs with non protein coding targets.