in (a) was slightly less significant at rs1206131 and the most significant SNP was downstream, which is also under the iHS and XP-EHH peaks from Africans in the HGDP and HapMap data. The graph of HGDP allele frequencies at this SNP shows that the ancestral T allele has increased frequencies throughout Africa relative to other major global populations (Supplementary Figure 7). Average (standard deviation, maximum) Fst values in this region between YRI and African American were 0.001(0.001, 0.015), between YRI and CEU were 0.040 (0.045, 0.304), and between African American and CEU were 0.011(0.013, 0.082).
